Starring: Thomas Jane, Saffron Burrows, Samuel L. Jackson, Jacqueline McKenzie, Michael Rapaport, Stellan Skarsgård, LL Cool J

What’s the old adage? Never genetically modify something that might want to eat you? Obviously, the researchers on board the sea bound laboratory Aquatica never heard that bit of advice. On the hunt for a cure for Alzheimer’s disease, the researchers mine the brain fluid of three genetically modified sharks whose brains grow larger and craftier by the day. When the largest of sharks manages to break free, it heads off on a crusade to free the other imprisoned sharks while eating just about everything that gets in its way. Run, LL Cool J!